Application of an Asthma Screening Questionnaire in Children with Sickle Cell Disease.

ABSTRACT: Objective: Asthma in sickle cell disease (SCD) patients is associated with elevated morbidity and mortality. Early detection and initiation of treatment may therefore lead to improved outcome. Utility of an asthma screening questionnaire to identify obstructive airway disease and physician diagnosed asthma in children with SCD at an outpatient setting as an effective, easy-to-administer screening tool has not previously been evaluated in this population. Methods: A previously validated asthma screening questionnaire and spirometry were prospectively administered to 41 SCD children at a routine clinic visit. Results: Prevalence of obstructive airway was 51.2% (n = 21) and physician diagnosis of asthma 33.3% (n = 13). Sensitivity (40%)

SUBMITTER: Yadav A 

PROVIDER: S-EPMC4580138 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature