Cytomegalovirus infection can mimic genetic nephrotic syndrome: a case report.

ABSTRACT:

Background

Nephrotic syndrome is a relatively rare but serious condition in children. Infantile nephrotic syndrome often has a genetic origin; the treatment is then symptomatic, with a poor prognosis, and a rapid evolution to chronic kidney disease. However, non-genetic infantile nephrotic syndrome has been identified. Here we report for the first time in a child a nephrotic syndrome as the sole clinical expression of a cytomegalovirus infection.

Case presentation

The patient was 5 months old when he presented with a nephrotic syndrome. An exhaustive genetic testing was conducted and came back negative. A viral work-up only showed a positive cytomegalovirus PCR. Antiviral treatment lead to a complete remission of the nephrotic syndrome, with no requirement for steroid therap

SUBMITTER: Hogan J 

PROVIDER: S-EPMC4580224 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature