Long-term adverse outcomes in survivors of childhood bone sarcoma: the British Childhood Cancer Survivor Study.

ABSTRACT:

Background

With improved survival, more bone sarcoma survivors are approaching middle age making it crucial to investigate the late effects of their cancer and its treatment. We investigated the long-term risks of adverse outcomes among 5-year bone sarcoma survivors within the British Childhood Cancer Survivor Study.

Methods

Cause-specific mortality and risk of subsequent primary neoplasms (SPNs) were investigated for 664 bone sarcoma survivors. Use of health services, health and marital status, alcohol and smoking habits, and educational qualifications were investigated for survivors who completed a questionnaire.

Results

Survivors were seven times more likely to experience all-cause mortality than expected, and there were substantial differences in risk depending on

SUBMITTER: Fidler MM 

PROVIDER: S-EPMC4580396 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature