5-Fluorouracil "Chemowraps" in the Treatment of Multiple Actinic Keratoses: A Norwich Experience.

ABSTRACT:

Introduction

Topical 5-fluorouracil (5-FU) has been used to treat actinic keratosis for decades. It has been an important and effective treatment which the patient can self-administer, but is limited by the surface area of skin to be treated (according to the manufacturer's guidelines) of 500 cm(2). Other topical treatments can be painful, or require hospital/health care professional input. The use of 5-FU under occlusion (chemowraps) for large areas of sun-damaged skin on the arms or legs has been described and is a potentially useful treatment option. We describe our experiences with this technique in the Norfolk and Norwich University Hospital Dermatology Department (Norwich, UK).

Methods

Five patients were recruited into this pilot study. Topical 5-FU was applied to sun-

SUBMITTER: Goon PK 

PROVIDER: S-EPMC4580657 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature