Albuminuria, renal dysfunction and circadian blood pressure rhythm in older men: a population-based longitudinal cohort study.

ABSTRACT:

Background

Both albuminuria and kidney dysfunction may affect circadian blood pressure (BP) rhythm, while exacerbating each other's effects. We investigated associations and interactions of these two risk factors with circadian BP rhythm variation and non-dipper pattern progression in community-dwelling older men.

Methods

This was a cross-sectional and longitudinal analyses in the third and fourth cycles of the Uppsala Longitudinal Study of Adult Men, including 1051 men (age 71 years) with assessments on urinary albumin excretion rate (UAER), 24-h ambulatory BP monitoring (ABPM) and cystatin-C-estimated glomerular filtration rate (eGFR). Of these, 574 men attended re-examination after 6 years. Study outcomes were ABMP changes and non-dipping BP pattern (prevalence and progre

SUBMITTER: Xu H 

PROVIDER: S-EPMC4581386 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature