Effect of probiotic chewing tablets on early childhood caries--a randomized controlled trial.

ABSTRACT:

Background

To evaluate the effect of probiotic chewing tablets on early childhood caries development in preschool children living in a low socioeconomic multicultural area.

Methods

The investigation employed a randomized double-blind placebo-controlled design. The study group consisted of 138 healthy 2-3-year-old children that were consecutively recruited after informed parental consent. After enrollment, they were randomized to a test or a placebo group. The parents of the test group were instructed to give their child one chewing tablet per day containing three strains of live probiotic bacteria (ProBiora3) and the placebo group got identical tablets without bacteria. The duration was one year and the prevalence and increment of initial and manifest caries lesions was exam

SUBMITTER: Hedayati-Hajikand T 

PROVIDER: S-EPMC4583156 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature