Developmental Markers Expressed in Neocortical Layers Are Differentially Exhibited in Olfactory Cortex.

ABSTRACT: Neurons in the cerebral cortex stratify on the basis of their time of origin, axonal terminations and the molecular identities assigned during early development. Olfactory cortices share many feature with the neocortex, including clear lamination and similar cell types. The present study demonstrates that the markers differentially expressed in the projection neurons of the cerebral cortex are also found in olfactory areas. Three of the four regions examined (pars principalis of the anterior olfactory nucleus: AONpP, anterior and posterior piriform cortices: APC, PPC, and the olfactory tubercle) expressed transcription factors found in deep or superficial neurons in the developing neocortex, though large differences were found between areas. For example, while the AONpP, APC and PPC all br

SUBMITTER: Brunjes PC 

PROVIDER: S-EPMC4583488 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature