Longitudinal measures of perfluoroalkyl substances (PFAS) in serum of Gullah African Americans in South Carolina: 2003-2013.

ABSTRACT:

Background

Charleston Harbor has elevated concentrations of PFAS in dolphins, but local human exposure data are limited.

Objectives

We sought to describe PFAS serum concentrations' temporal trends among Gullah African American residents of coastal South Carolina.

Methods

Longitudinal measures of PFAS in blood serum from a Gullah clinical sample, without lupus, were examined using spaghetti plots and visit-to-visit change scores (e.g., differences in concentrations between visits) among the 68 participants with repeated measures available. We also modeled population-level trends among the 71 participants with any data using proportionate percentile models, accounting for clustering through robust standard errors. In a post-hoc analysis we examined heterogeneity of temp

SUBMITTER: Gribble MO 

PROVIDER: S-EPMC4583839 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature