Multi-Stacked Supported Lipid Bilayer Micropatterning through Polymer Stencil Lift-Off.

ABSTRACT: Complex multi-lamellar structures play a critical role in biological systems, where they are present as lamellar bodies, and as part of biological assemblies that control energy transduction processes. Multi-lamellar lipid layers not only provide interesting systems for fundamental research on membrane structure and bilayer-associated polypeptides, but can also serve as components in bioinspired materials or devices. Although the ability to pattern stacked lipid bilayers at the micron scale is of importance for these purposes, limited work has been done in developing such patterning techniques. Here, we present a simple and direct approach to pattern stacked supported lipid bilayers (SLBs) using polymer stencil lift-off and the electrostatic interactions between cationic and anionic lipids

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC4584287 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature