High-Resolution Mapping of Myeloarchitecture In Vivo: Localization of Auditory Areas in the Human Brain.

ABSTRACT: The precise delineation of auditory areas in vivo remains problematic. Histological analysis of postmortem tissue indicates that the relation of areal borders to macroanatomical landmarks is variable across subjects. Furthermore, functional parcellation schemes based on measures of, for example, frequency preference (tonotopy) remain controversial. Here, we propose a 7 Tesla magnetic resonance imaging method that enables the anatomical delineation of auditory cortical areas in vivo and in individual brains, through the high-resolution visualization (0.6 × 0.6 × 0.6 mm(3)) of intracortical anatomical contrast related to myelin. The approach combines the acquisition and analysis of images with multiple MR contrasts (T1, T2*, and proton density). Compared with previous methods, the proposed s

SUBMITTER: De Martino F 

PROVIDER: S-EPMC4585494 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature