Neuroanatomy of Individual Differences in Language in Adult Males with Autism.

ABSTRACT: One potential source of heterogeneity within autism spectrum conditions (ASC) is language development and ability. In 80 high-functioning male adults with ASC, we tested if variations in developmental and current structural language are associated with current neuroanatomy. Groups with and without language delay differed behaviorally in early social reciprocity, current language, but not current autistic features. Language delay was associated with larger total gray matter (GM) volume, smaller relative volume at bilateral insula, ventral basal ganglia, and right superior, middle, and polar temporal structures, and larger relative volume at pons and medulla oblongata in adulthood. Despite this heterogeneity, those with and without language delay showed significant commonality in morphometri

SUBMITTER: Lai MC 

PROVIDER: S-EPMC4585508 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature