Genomic and transcriptomic insights into the efficient entomopathogenicity of Bacillus thuringiensis.

ABSTRACT: Bacillus thuringiensis has been globally used as a microbial pesticide for over 70 years. However, information regarding its various adaptions and virulence factors and their roles in the entomopathogenic process remains limited. In this work, we present the complete genomes of two industrially patented Bacillus thuringiensis strains (HD-1 and YBT-1520). A comparative genomic analysis showed a larger and more complicated genome constitution that included novel insecticidal toxicity-related genes (ITRGs). All of the putative ITRGs were summarized according to the steps of infection. A comparative genomic analysis showed that highly toxic strains contained significantly more ITRGs, thereby providing additional strategies for infection, immune evasion, and cadaver utilization. Furthermore, a

SUBMITTER: Zhu L 

PROVIDER: S-EPMC4585936 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature