Baseline Ultrasound and Clinical Correlates in Children with Cystic Fibrosis.

ABSTRACT:

Objective

To investigate the relationship between abdominal ultrasound findings and demographic, historical, and clinical features in children with cystic fibrosis (CF).

Study design

Children age 3-12 years with CF without known cirrhosis, were enrolled in a prospective, multicenter study of ultrasound to predict hepatic fibrosis. Consensus ultrasound patterns were assigned by 3 radiologists as normal, heterogeneous, homogeneous, or cirrhosis. Data were derived from direct collection and US or Toronto CF registries. χ(2) or ANOVA were used to compare variables among ultrasound groups and between normal and abnormal. Logistic regression was used to study risk factors for having abnormal ultrasound.

Results

Findings in 719 subjects were normal (n = 590, 82.1%), heteroge

SUBMITTER: Leung DH 

PROVIDER: S-EPMC4586395 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature