Usual blood pressure, peripheral arterial disease, and vascular risk: cohort study of 4.2 million adults.

ABSTRACT:

Objectives

To determine the subgroup specific associations between usual blood pressure and risk of peripheral arterial disease, and to examine the relation between peripheral arterial disease and a range of other types of vascular disease in a large contemporary cohort.

Design

Cohort study.

Setting

Linked electronic health records from 1990 to 2013 in the United Kingdom.

Participants

4,222,459 people aged 30-90 years, registered at a primary care practice for at least one year and with a blood pressure measurement.

Main outcome measures

Time to first diagnosis of new onset peripheral arterial disease and time to first diagnosis of 12 different vascular events.

Results

A 20 mm Hg higher than usual systolic blood pressure was associated with a 63%

SUBMITTER: Emdin CA 

PROVIDER: S-EPMC4586462 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature