Bladder Function After Fetal Surgery for Myelomeningocele.

ABSTRACT:

Background

A substudy of the Management of Myelomeningocele Study evaluating urological outcomes was conducted.

Methods

Pregnant women diagnosed with fetal myelomeningocele were randomly assigned to either prenatal or standard postnatal surgical repair. The substudy included patients randomly assigned after April 18, 2005. The primary outcome was defined in their children as death or the need for clean intermittent catheterization (CIC) by 30 months of age characterized by prespecified criteria. Secondary outcomes included bladder and kidney abnormalities observed by urodynamics and renal/bladder ultrasound at 12 and 30 months, which were analyzed as repeated measures.

Results

Of the 115 women enrolled in the substudy, the primary outcome occurred in 52% of children i

SUBMITTER: Brock JW 

PROVIDER: S-EPMC4586733 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature