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ABSTRACT: Objective
Diet modification is recommended to treat childhood cardiovascular (CV) risk factors; however, the optimal dietary strategy is unknown.Methods
In a randomized trial, the effect of a low-fat (LF) and a low-glycemic-load (LGL) reduced-calorie diet were examined in youth with overweight/obesity with CV risk factors. Using a novel intervention, we delivered LF or LGL meals and nutrition education to the home for 8 weeks (Intensive Phase), followed by 4 months Maintenance without food provision. Between-group differences in the change in insulin area under the curve (InsAUC) by oral glucose tolerance test and other risk factors were analyzed.Results
Overall, participants (n = 27) showed substantial improvement during the Intensive Phase, including InsAUC (-59 ±
SUBMITTER: de Ferranti SD
PROVIDER: S-EPMC4586898 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature