Non-exercise physical activity attenuates motor symptoms in Parkinson disease independent from nigrostriatal degeneration.

ABSTRACT:

Objective

To investigate the relationship between time spent in non-exercise and exercise physical activity and severity of motor functions in Parkinson disease (PD).

Background

Increasing motor impairments of PD incline many patients to a sedentary lifestyle. We investigated the relationship between duration of both non-exercise and exercise physical activity over a 4-week period using the Community Health Activities Model Program for Seniors (CHAMPS) questionnaire and severity of clinical motor symptoms in PD. We accounted for the magnitude of nigrostriatal degeneration.

Methods

Cross-sectional study. PD subjects, n = 48 (40 M); 69.4 ± 7.4 (56-84) years old; 8.4 ± 4.2 (2.5-20) years motor disease duration, mean UPDRS motor score 27.5 ± 10.3 (7-53) and mean MMSE scor

SUBMITTER: Snider J 

PROVIDER: S-EPMC4587298 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature