Genome expansion in bacteria: the curios case of Chlamydia trachomatis.

ABSTRACT:

Background

Recent findings indicated that a correlation between genomic % AT and genome size within strains of microbial species was predominantly associated with the uptake of foreign DNA. One species however, Chlamydia trachomatis, defied any explanation. In the present study 79 fully sequenced C. trachomatis genomes, representing ocular- (nine strains), urogenital- (36 strains) and lymphogranuloma venereum strains (LGV, 22 strains), in three pathogroups, in addition to 12 laboratory isolates, were scrutinized with the intent of elucidating the positive correlation between genomic AT content and genome size.

Results

The average size difference between the strains of each pathogroup was largely explained by the incorporation of genetic fragments. These fragments were slight

SUBMITTER: Bohlin J 

PROVIDER: S-EPMC4589037 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature