Trail Making Test Elucidates Neural Substrates of Specific Poststroke Executive Dysfunctions.

ABSTRACT:

Background and purpose

Poststroke cognitive impairment is typified by prominent deficits in processing speed and executive function. However, the underlying neuroanatomical substrates of executive deficits are not well understood, and further elucidation is needed. There may be utility in fractionating executive functions to delineate neural substrates.

Methods

One test amenable to fine delineation is the Trail Making Test (TMT), which emphasizes processing speed (TMT-A) and set shifting (TMT-B-A difference, proportion, quotient scores, and TMT-B set-shifting errors). The TMT was administered to 2 overt ischemic stroke cohorts from a multinational study: (1) a chronic stroke cohort (N=61) and (2) an acute-subacute stroke cohort (N=45). Volumetric quantification of ischemic s

SUBMITTER: Muir RT 

PROVIDER: S-EPMC4589519 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature