Chikungunya viral arthritis in the United States: a mimic of seronegative rheumatoid arthritis.

ABSTRACT:

Objective

Chikungunya virus (CHIKV) is an arthritogenic mosquito-transmitted alphavirus that spread to the Caribbean in 2013 and to the US in 2014. CHIKV-infected patients develop inflammatory arthritis that can persist for months or years, but little is known about the rheumatologic and immunologic features of CHIKV-related arthritis in humans, particularly as compared to rheumatoid arthritis (RA). The purpose of this study was to describe these features in a group of 10 American travelers who were nearly simultaneously infected while visiting Haiti in June 2014.

Methods

Patient history was obtained and physical examination and laboratory tests were performed. All patients with CHIKV-related arthritis had detectable levels of anti-CHIKV IgG. Using cytometry by time-of-fligh

SUBMITTER: Miner JJ 

PROVIDER: S-EPMC4591551 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature