Overall and central adiposity and breast cancer risk in the Sister Study.

ABSTRACT:

Background

Greater body mass index (BMI), a measure of overall adiposity, is associated with a higher risk of postmenopausal breast cancer. The role of central adiposity, often measured by waist circumference, is less well understood, especially among premenopausal women. The objective of the current study was to examine multiple measures of adiposity in relation to breast cancer in a prospective cohort study.

Methods

A total of 50,884 Sister Study cohort participants aged 35 to 74 years were enrolled from 2003 through 2009. Inclusion criteria for the cohort included having a sister previously diagnosed with breast cancer. Trained study personnel measured height, weight, and waist and hip circumference during a home visit and study participants completed a detailed questionn

SUBMITTER: White AJ 

PROVIDER: S-EPMC4592412 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature