Distinct neural correlates for attention lapses in patients with schizophrenia and healthy participants.

ABSTRACT: Momentary lapses in attention are common in healthy populations. This phenomenon has recently received increased investigation, particularly in relationship to the default mode network (DMN). Previous research has suggested that these lapses may be due to intrusive task-irrelevant thoughts. The study of this phenomenon in schizophrenia, which is characterized by a wide variety of cognitive deficits including deficits in attention, has not previously been explored. We used the AX Continuous Performance Task to investigate attention lapses in healthy participants as well as patients with schizophrenia. We found distinct patterns of network activation between these two groups. Lapses in healthy participants were associated with DMN activation, while in patients, the same behavioral phenomenon

SUBMITTER: Phillips RC 

PROVIDER: S-EPMC4594500 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature