Influence of tumour stage at breast cancer detection on survival in modern times: population based study in 173,797 patients.

ABSTRACT:

Objectives

To assess the influence of stage at breast cancer diagnosis, tumour biology, and treatment on survival in contemporary times of better (neo-)adjuvant systemic therapy.

Design

Prospective nationwide population based study.

Setting

Nationwide Netherlands Cancer Registry.

Participants

Female patients with primary breast cancer diagnosed between 1999 and 2012 (n=173,797), subdivided into two time cohorts on the basis of breast cancer diagnosis: 1999-2005 (n=80,228) and 2006-12 (n=93,569).

Main outcome measures

Relative survival was compared between the two cohorts. Influence of traditional prognostic factors on overall mortality was analysed with Cox regression for each cohort separately.

Results

Compared with 1999-2005, patients from 2006-

SUBMITTER: Saadatmand S 

PROVIDER: S-EPMC4595560 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature