Sex differences in outcomes of methadone maintenance treatment for opioid use disorder: a systematic review and meta-analysis.

ABSTRACT:

Background

Opioid use disorder is a serious international concern with limited treatment success. Men and women differ in their susceptibility to opioid use disorder and response to methadone treatment and can therefore benefit from sex-specific treatment. We performed a systematic review of the literature on outcomes of methadone maintenance treatment for opioid use disorder in men and women related to drug use, health status and social functioning.

Methods

We searched PubMed, Embase, PsycINFO and CINAHL for observational or randomized controlled studies involving adults 18 years of age or older undergoing methadone treatment for opioid use disorder. Studies were included if they investigated sex differences in methadone treatment outcomes. Two authors independently reviewe

SUBMITTER: Bawor M 

PROVIDER: S-EPMC4596116 | biostudies-literature | 2015 Jul-Sep

REPOSITORIES: biostudies-literature