Effect of Antiepileptic Drugs for Acute and Chronic Seizures in Children with Encephalitis.

ABSTRACT:

Background

Encephalitis presents with seizures in the acute phase and increases the risk of late unprovoked seizures and epilepsy. This study aimed to evaluate the effect of antiepileptic drugs in pediatric patients with acute seizures due to encephalitis and epilepsy.

Patients and methods

Cases of acute pediatric encephalitis between January 2000 and December 2010 were reviewed. Clinical data, including onset at age, seizure type, seizure frequency, effects of antiepileptic drugs, and prognosis were analyzed.

Results

During the study period, 1038 patients (450 girls, 588 boys) were enrolled. Among them, 44.6% (463) had seizures in the acute phase, 33% had status epilepticus, and 26% (251) developed postencephalitic epilepsy. At one year of follow-up, 205 of the 251 p

SUBMITTER: Lin KL 

PROVIDER: S-EPMC4596539 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature