Predicting Falls in Parkinson Disease: What Is the Value of Instrumented Testing in OFF Medication State?

ABSTRACT:

Background

Falls are a common complication of advancing Parkinson's disease (PD). Although numerous risk factors are known, reliable predictors of future falls are still lacking. The objective of this prospective study was to investigate clinical and instrumented tests of balance and gait in both OFF and ON medication states and to verify their utility in the prediction of future falls in PD patients.

Methods

Forty-five patients with idiopathic PD were examined in defined OFF and ON medication states within one examination day including PD-specific clinical tests, instrumented Timed Up and Go test (iTUG) and computerized dynamic posturography. The same gait and balance tests were performed in 22 control subjects of comparable age and sex. Participants were then followed-up f

SUBMITTER: Hoskovcova M 

PROVIDER: S-EPMC4596567 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature