A systematic review of dietary, nutritional, and physical activity interventions for the prevention of prostate cancer progression and mortality.

ABSTRACT:

Purpose

Given the long-term, although potentially fatal, nature of prostate cancer, there is increasing observational evidence for the reduction in disease progression and mortality through changes in lifestyle factors.

Methods

We systematically reviewed dietary, nutritional, and physical activity randomized interventions aimed at modifying prostate cancer progression and disease-specific mortality, including a detailed assessment of risk of bias and methodological quality.

Results

Forty-four randomized controlled trials of lifestyle interventions, with prostate cancer progression or mortality outcomes, were identified. Substantial heterogeneity of the data prevented a meta-analysis. The included trials involved 3,418 prostate cancer patients, median 64 men per trial,

SUBMITTER: Hackshaw-McGeagh LE 

PROVIDER: S-EPMC4596907 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature