Estimating the Distribution of the Incubation Periods of Human Avian Influenza A(H7N9) Virus Infections.

ABSTRACT: A novel avian influenza virus, influenza A(H7N9), emerged in China in early 2013 and caused severe disease in humans, with infections occurring most frequently after recent exposure to live poultry. The distribution of A(H7N9) incubation periods is of interest to epidemiologists and public health officials, but estimation of the distribution is complicated by interval censoring of exposures. Imputation of the midpoint of intervals was used in some early studies, resulting in estimated mean incubation times of approximately 5 days. In this study, we estimated the incubation period distribution of human influenza A(H7N9) infections using exposure data available for 229 patients with laboratory-confirmed A(H7N9) infection from mainland China. A nonparametric model (Turnbull) and several param

SUBMITTER: Virlogeux V 

PROVIDER: S-EPMC4597801 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature