The Effects of Season of Birth on the Inflammatory Response to Psychological Stress in Hainan Island, China.

ABSTRACT: Season of birth (SOB) has been investigated as one of the environmental factors that might epigenetically determine the physiology of individuals. This study investigated the role of SOB in the association between Quality of Life (QOL), a proxy of psychological stress status, and C-reactive protein (CRP) concentration (i.e., inflammatory status) among 1,085 adults (aged 20-57 years old) in Hainan Island, China. High sensitivity CRP concentration was measured in dried blood spot samples, while the abbreviated version of the World Health Organization's QOL questionnaire was used to gather information on six QOL domains. Analysis stratified by three historically distinct age groups revealed a significant association between CRP concentration, SOB, QOL and an interaction between SOB and QOL am

SUBMITTER: Yazawa A 

PROVIDER: S-EPMC4598090 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature