Investigation of Pneumocystis jirovecii colonization in patients with chronic pulmonary diseases in the People's Republic of China.

ABSTRACT:

Background

The detection of Pneumocystis jirovecii DNA in respiratory specimen from individuals who do not have signs or symptoms of pneumonia has been defined as colonization. The role of P. jirovecii colonization in the development or progression of various lung diseases has been reported, but little information about P. jirovecii colonization in patients is available in the People's Republic of China.

Objective

To determine the prevalence of P. jirovecii colonization in patients with various pulmonary diseases, including the acute and stable stage of COPD, interstitial lung diseases, cystic fibrosis, and chronic bronchiectasis.

Materials and methods

A loop-mediated isothermal amplification (LAMP) and a conventional polymerase chain reaction (PCR) method for detecti

SUBMITTER: Wang DD 

PROVIDER: S-EPMC4598221 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature