Venous thromboembolism and subsequent risk of cancer in patients with liver disease: a population-based cohort study.

ABSTRACT:

Objective

Venous thromboembolism (VTE) may be a marker of occult cancer in the general population. While liver disease is known to increase the risk of VTE and cancer, it is unclear whether VTE in patients with liver disease is also a marker of occult cancer.

Design

A population-based cohort study.

Setting

Denmark.

Participants

We used population-based health registries to identify all patients with liver disease in Denmark with a first-time diagnosis of VTE (including superficial or deep venous thrombosis and pulmonary embolism) during 1980-2010. Patients with non-cirrhotic liver disease and patients with liver cirrhosis were followed as two separate cohorts from the date of their VTE.

Measures

For each cohort, we computed the absolute and relative risk

SUBMITTER: Montomoli J 

PROVIDER: S-EPMC4599159 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature