Outcome Reporting in Cardiac Surgery Trials: Systematic Review and Critical Appraisal.

ABSTRACT:

Background

There is currently no accepted standard for reporting outcomes following cardiac surgery. The objective of this paper was to systematically review the literature to evaluate the current use and definition of perioperative outcomes reported in cardiac surgery trials.

Methods and results

We reviewed 5 prominent medical and surgical journals on Medline from January 1, 2010, to June 30, 2014, for randomized controlled trials involving coronary artery bypass grafting and/or valve surgery. We identified 34 trials meeting inclusion criteria. Sample sizes ranged from 57 to 4752 participants (median 351). Composite end points were used as a primary outcome in 56% (n=19) of the randomized controlled trials and as a secondary outcome in 12% (n=4). There were 14 different com

SUBMITTER: Goldfarb M 

PROVIDER: S-EPMC4599473 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature