The early immune response to infection of chickens with Infectious Bronchitis Virus (IBV) in susceptible and resistant birds.

ABSTRACT:

Background

Infectious Bronchitis is a highly contagious respiratory disease which causes tracheal lesions and also affects the reproductive tract and is responsible for large economic losses to the poultry industry every year. This is due to both mortality (either directly provoked by IBV itself or due to subsequent bacterial infection) and lost egg production. The virus is difficult to control by vaccination, so new methods to curb the impact of the disease need to be sought. Here, we seek to identify genes conferring resistance to this coronavirus, which could help in selective breeding programs to rear chickens which do not succumb to the effects of this disease.

Methods

Whole genome gene expression microarrays were used to analyse the gene expression differences, which o

SUBMITTER: Smith J 

PROVIDER: S-EPMC4600211 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature