Hierarchical organization of long-range circuits in the olfactory cortices.

ABSTRACT: How sensory information is processed within olfactory cortices is unclear. Here, we examined long-range circuit wiring between different olfactory cortical regions of acute mouse brain slices using a channelrhodopsin-2 (ChR2)-based neuronal targeting approach. Our results provide detailed information regarding the synaptic properties of the reciprocal long-range monosynaptic glutamatergic projections (LRMGP) between and within anterior piriform cortex (aPC), posterior piriform cortex (pPC), and lateral entorhinal cortex (LEC), thereby creating a long-range inter- and intracortical circuit diagrams at the level of synapses and single cortical neurons. Our results reveal the following information regarding hierarchical intra- and intercortical organizations: (i) there is massive bottom-up (i

SUBMITTER: Yang W 

PROVIDER: S-EPMC4600391 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature