1.25 A resolution structure of an RNA 20-mer that binds to the TREX2 complex.

ABSTRACT: The 1.25 Å resolution H32:R crystal structure of a 20 nt ribonucleotide that binds to the TREX-2 complex with high affinity shows a double-stranded RNA duplex arranged along a crystallographic 31 axis in which the antiparallel chains overlap by 18 nucleotides and are related by a crystallographic twofold axis. The duplex shows C-A, U-U and C-C noncanonical base pairings together with canonical Watson-Crick A-U and G-C pairs and a G-U wobble.

SUBMITTER: Valkov E 

PROVIDER: S-EPMC4601597 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature