Hepatitis C Virus Reinfection and Spontaneous Clearance of Reinfection--the InC3 Study.

ABSTRACT:

Background

We aimed to characterize the natural history of hepatitis C virus (HCV) reinfection and spontaneous clearance following reinfection (reclearance), including predictors of HCV reclearance.

Methods

Data were synthesized from the 9 prospective cohorts of the International Collaboration of Incident Human Immunodeficiency Virus and HCV in Injecting Cohorts study, which evaluated HCV infection outcomes among people who inject drugs. Participants with primary HCV infection were classified as having achieved viral suppression if they had negative results of at least 1 subsequent HCV RNA test. Those with positive results of an HCV RNA test following viral suppression were investigated for reinfection. Viral sequence analysis was used to identify reinfection (defined as det

SUBMITTER: Sacks-Davis R 

PROVIDER: S-EPMC4601911 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature