Different Candida parapsilosis clinical isolates and lipase deficient strain trigger an altered cellular immune response.

ABSTRACT: Numerous human diseases can be associated with fungal infections either as potential causative agents or as a result of changed immune status due to a primary disease. Fungal infections caused by Candida species can vary from mild to severe dependent upon the site of infection, length of exposure, and past medical history. Patients with impaired immune status are at increased risk for chronic fungal infections. Recent epidemiologic studies have revealed the increasing incidence of candidiasis caused by non-albicans species such as Candida parapsilosis. Due to its increasing relevance we chose two distinct C. parapsilosis strains, to describe the cellular innate immune response toward this species. In the first section of our study we compared the interaction of CLIB 214 and GA1 cells with

SUBMITTER: Toth R 

PROVIDER: S-EPMC4602145 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature