Distinct aetiopathogenesis in subgroups of functional dyspepsia according to the Rome III criteria.

ABSTRACT:

Background and objective

Whether there is distinct pathogenesis in subgroups of functional dyspepsia (FD), the postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS) remains controversial. We aimed to identify the risk factors of FD and its subgroups in the Chinese population.

Methods

Patients with dyspepsia and healthy subjects who underwent gastric cancer screening were enrolled in this multicentre study from 2010 to 2012. All patients were evaluated by questionnaire, oesophagoduodenoscopy, histological examination and Helicobacter pylori tests. Subgroups of FD were classified according to the Rome III criteria. Psychiatric stress was assessed by the short form Brief Symptom Rating Scale. CagA and VacA genotypes were determined by PCR.

Results

Of 23

SUBMITTER: Fang YJ 

PROVIDER: S-EPMC4602241 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature