Detecting miRNA Mentions and Relations in Biomedical Literature.

ABSTRACT:

Introduction

MicroRNAs (miRNAs) have demonstrated their potential as post-transcriptional gene expression regulators, participating in a wide spectrum of regulatory events such as apoptosis, differentiation, and stress response. Apart from the role of miRNAs in normal physiology, their dysregulation is implicated in a vast array of diseases. Dissection of miRNA-related associations are valuable for contemplating their mechanism in diseases, leading to the discovery of novel miRNAs for disease prognosis, diagnosis, and therapy.

Motivation

Apart from databases and prediction tools, miRNA-related information is largely available as unstructured text. Manual retrieval of these associations can be labor-intensive due to steadily growing number of publications. Additionally, most

SUBMITTER: Bagewadi S 

PROVIDER: S-EPMC4602280 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature