NT-proBNP: is it a more significant risk factor for mortality than troponin T in incident hemodialysis patients?

ABSTRACT: Numerous studies have demonstrated that cardiac biomarkers are significant predictors of cardiovascular (CV) and all-cause mortality in ESRD patients, but most of the studies were retrospective or included small numbers of patients, only prevalent dialysis patients, or measured 1 or 2 biomarkers. This study was to analyze the association between 3 cardiac biomarkers and mortality in incident HD patients. A prospective cohort of 864 incident HD patients was followed for 30 months. Based on the median values of baseline NT-proBNP, cTnT, and hsCRP, the patients were divided into "high" and "low" groups, and CV and all-cause mortality were compared between each group. Additionally, time-dependent ROC curves were constructed, and the NRI and IDI of the models with various biomarkers were calcul

SUBMITTER: Oh HJ 

PROVIDER: S-EPMC4602775 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature