Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial.

ABSTRACT: The primary objective in the study is determination of efficacy of probiotic preparation as a supportive therapy in eradication of Helicobacter pylori.The study was multicenter, prospective, randomized, placebo controlled, and double-blind. The subjects first filled out a specially designed questionnaire to assess the severity of the 10 symptoms, which can be related to eradication therapy to be monitored during the trial. Each subject then received 28 capsules of probiotic preparation or matching placebo capsules, which they were supposed to take over the following 14 days, twice a day, at least 2 hours prior to or after the antibiotic therapy administration.A total of 804 patients were enrolled in the trial, of which 650 (80.85%) were included in the analysis. The results show a signific

SUBMITTER: Hauser G 

PROVIDER: S-EPMC4603068 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature