Thermodynamics of Self-Assembly of Dicarboxylate Ions with Binuclear Lanthanide Complexes.

ABSTRACT: Self-assembly of a range of carboxylic acids (benzoic acid, dinicotinic acid, nicotinic acid, and isophthalic acid) with the europium complex of 5-nitro-α,α'-bis(DO3Ayl)-m-xylene (where DO3A is 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid) has been explored to establish the thermodynamics of binding in a range of solvent systems and in a range of aqueous buffer solutions. In this system, profound effects are observed as a consequence of competition by the hydroxide ion, which outcompetes even dinicotinate at high pH. In the case of isophthalate, which binds most strongly, and dinicotinate, both enthalpic and entropic contributions to binding have been identified. The europium complex with 5-nitro-α,α'-bis(DO3Ayl)-m-xylene is found to have a solution structure significantly different

SUBMITTER: Sorensen TJ 

PROVIDER: S-EPMC4603413 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature