Diabetes and cognitive decline in a French cohort of patients infected with HIV-1.

ABSTRACT:

Objective

We investigated the relationship of diabetes and prediabetes with cognitive performances, assessed through raw test and z scores and according to neurocognitive impairment (NCI) classification in a cohort of individuals infected with HIV.

Methods

The ANRS CO3 Aquitaine cohort is a prospective hospital-based cohort of HIV-1-infected patients under routine clinical management in 6 public hospitals in southwestern France. Between 2007 and 2009, an ancillary study consisted of a neuropsychological battery of 10 tests at baseline and 2-year follow-up. The severity of NCI (normal, asymptomatic, mild, HIV dementia) was assessed according to international guidelines.

Results

At baseline (400 patients, 33 with prediabetes, 39 with diabetes), in cross-sectional multiv

SUBMITTER: Dufouil C 

PROVIDER: S-EPMC4603596 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature