Recurrent stroke in childhood cancer survivors.

ABSTRACT:

Objective

To estimate the rates and predictors of recurrent stroke among survivors of pediatric cancer who have had a first stroke.

Methods

The Childhood Cancer Survivor Study is a retrospective cohort study with longitudinal follow-up that enrolled 14,358 survivors (<21 years old at diagnosis; diagnosed 1970-1986; survived ≥5 years after cancer diagnosis) and followed them prospectively since 1994. We surveyed 443 survivors who reported a first stroke to identify recurrent stroke, and estimated recurrent stroke rates ≥5 years after cancer diagnosis.

Results

Among 329 respondents (74% response rate), 271 confirmed a first stroke at a median age of 19 years (range 0-53), and 70 reported a second stroke at a median age of 32 years (range 1-56). In a multivariable Cox pr

SUBMITTER: Fullerton HJ 

PROVIDER: S-EPMC4603599 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature