Age-Related Changes in Corneal Deformation Dynamics Utilizing Scheimpflug Imaging.

ABSTRACT:

Purpose

To study age-related changes in corneal deformation response to air-puff applanation tonometry.

Methods

Fifty healthy subjects were recruited for a prospective study and divided into two equal age groups (≤ 28 and ≥ 50 years old). Up to three measurements by a corneal deformation analyser based on the Scheimpflug principle were performed on the left eye of each subject. Raw Scheimpflug images were used to extract changes in anterior and posterior corneal profiles, which were further modelled by an orthogonal series of Chebyshev polynomial functions. Time series of the polynomial coefficients of even order exhibited a dynamic behavior in which three distinct stages were recognized. A bilinear function was used to model the first and the third stage of corneal dynamics

SUBMITTER: Rogowska ME 

PROVIDER: S-EPMC4604157 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature