A Randomized Comparative Effectiveness Trial for Preventing Type 2 Diabetes.

ABSTRACT:

Objectives

We evaluated the weight loss effectiveness of a YMCA model for the Diabetes Prevention Program (DPP) lifestyle intervention.

Methods

Between July 2008 and November 2010, we individually randomized 509 overweight or obese, low-income, nondiabetic adults with elevated blood glucose in Indianapolis, Indiana, to receive standard care plus brief lifestyle counseling or be offered a group-based YMCA adaptation of the DPP (YDPP). Primary outcome was mean weight loss difference at 12 months. In our intention-to-treat analyses, we used longitudinal linear or logistic regression, multiply imputing missing observations. We used instrumental variables regression to estimate weight loss effectiveness among participants completing 9 or more intervention lessons.

Results

SUBMITTER: Ackermann RT 

PROVIDER: S-EPMC4605179 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature