Presence of pathogenicity island related and plasmid encoded virulence genes in cytolethal distending toxin producing Escherichia coli isolates from diarrheal cases.

ABSTRACT:

Context

Mobile genetic elements such as plasmids, bacteriophages, insertion elements, and genomic islands play a critical role in virulence of bacterial pathogens. These elements transfer horizontally and could play an important role in the evolution and virulence of many pathogens. A broad spectrum of gram-negative bacterial species has been shown to produce a cytolethal distending toxin (CDT). On the other hand, Shiga toxin producing Escherichia coli are the one carry virulence genes such as stx 1 and stx 2 (Shiga toxin) and these genes can be acquired by horizontal gene transfer.

Aim

The aim of this study was to investigate the presence of other virulence associated genes among CDT producing E. coli strains.

Materials and methods

Thirty CDT positive strains isolate

SUBMITTER: Oloomi M 

PROVIDER: S-EPMC4606577 | biostudies-literature | 2015 Sep-Dec

REPOSITORIES: biostudies-literature