Cancers in Australia in 2010 attributable to and prevented by the use of menopausal hormone therapy.

ABSTRACT:

Objectives

To estimate the proportion and number of cancers occurring in Australia in 2010 attributable to menopausal hormone therapy (MHT) use.

Methods

We estimated the population attributable fraction for cancers causally associated with MHT (breast, endometrium, ovary), and the proportion of colorectal cancers prevented by MHT. We used standard formulae incorporating Australian prevalence data, relative risks of cancer associated with MHT and cancer incidence. We also estimated potential change in cancer incidence under two hypothetical scenarios whereby 25% fewer Australian women used MHT, or women exclusively used oestrogen-only MHT.

Results

An estimated 539 cancers in Australia in 2010 were attributable to MHT: 453 breast, 67 endometrial and 19 ovarian cancers e

SUBMITTER: Jordan SJ 

PROVIDER: S-EPMC4606777 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature