Hemodynamic Features of Symptomatic Vertebrobasilar Disease.

ABSTRACT:

Background and purpose

Atherosclerotic vertebrobasilar disease is an important cause of posterior circulation stroke. To examine the role of hemodynamic compromise, a prospective multicenter study, Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke (VERiTAS), was conducted. Here, we report clinical features and vessel flow measurements from the study cohort.

Methods

Patients with recent vertebrobasilar transient ischemic attack or stroke and ≥50% atherosclerotic stenosis or occlusion in vertebral or basilar arteries (BA) were enrolled. Large-vessel flow in the vertebrobasilar territory was assessed using quantitative MRA.

Results

The cohort (n=72; 44% women) had a mean age of 65.6 years; 72% presented with ischemic stroke. Hypertension (9

SUBMITTER: Amin-Hanjani S 

PROVIDER: S-EPMC4607265 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature