Claustrum damage and refractory status epilepticus following febrile illness.

ABSTRACT:

Objective

To characterize the clinical, EEG, and brain imaging findings in an adult case series of patients with de novo refractory status epilepticus (SE) occurring after a febrile illness.

Methods

A retrospective study (2010-2013) was undertaken with the following inclusion criteria: (1) previously healthy adults with refractory SE; (2) seizure onset 0-21 days after a febrile illness; (3) lacking evidence of infectious agents in CSF; (4) no history of seizures (febrile or afebrile) or previous or concomitant neurologic disorder.

Results

Among 155 refractory SE cases observed in the study period, 6 patients (17-35 years old) fulfilled the inclusion criteria. Confusion and stupor were the most common symptoms at disease onset, followed after a few days by acute repeat

SUBMITTER: Meletti S 

PROVIDER: S-EPMC4607596 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature